Dr. Basit Zeshan

Dr. Basit Zeshan

Assistant Professor, HOD Microbiology

FLS

Faculty of Life Sciences

Dr. Basit Zeshan earned PhD in Microbiology & Immunology from Nanjing Agricultural University, China and MPhil in Microbiology from Quaid-I-Azam University, Islamabad. He has designed and evaluated adenovirus vector based recombinant vaccine in ovo first time for Infectious Bronchitis Virus. He was awarded Best International Graduate Award from Nanjing Agricultural University, China in 2010. He is recipient of the Young Scientist Award from Chinese Academy of Sciences (CAS) Beijing, China. He has published more than 25 research papers in esteemed peer reviewed National & International Journals and presented papers in more than 20 International Conferences. He is member of American Society for Microbiology (ASM), World Poultry Science Association (Malaysia branch) and Life-long member of Pakistan Veterinary Medical Council (PVMC), Islamabad. His area of research is understanding the molecular basis of resistance in major multidrug resistant microbes. He is developing novel molecular diagnostic assays and modern recombinant vaccines for the diagnosis and prevention of the major infectious diseases.

  • General Virology
  • Advanced Virology
  • Immunology
  • General Immunology

Education

PhD Microbiology & Immunology
Nanjing Agri. University, CHINA
2007-2010

MPhil Microbiology
Quaid-E-Azam University
2004-2006
DVM Veterinary Sciences
Gomal University
2000-2004
Intermediate
BISE, DG Khan
97-99
Matic
BISE, DG Khan
95-97

Experience

HOD/Assistant Professor (Present)
University of Central Punjab, Lahore
Assistant Professor
The University of Lahore (Lahore Campus)
Research Associate
Nanjing Agricultural University,  CHINA
Research Associate
NARC ISLAMABAD

Fellowships and Awards

S. No. Title of the Award Organization
1. Best international graduate award 2010 Nanjing Agricultural University, China.
2. Fellowship for Young International Scientists 2011 Chinese Academy of Sciences, Beijing China

Research Grants

Research Project Source Total Funds
1 Construction, immunogenicity and protective efficacy of the subunit vaccine using receptor binding domain (RBD) of nephrotropic infectious bronchitis virus Ministry of Education, China 3M PKR
2 Pathogencity of the influenza A virus to mice CAS, Beijing, China 1M PKR

PhD Thesis Title

  • Construction, immunogenicity and protective efficacy of the Spike glycoprotein (S1) of infectious bronchitis virus with a replication-defective adenovirus vector.

Conferences Participated

Conference Title Organizer Location Date Sponsoring Agency
5th Saudi Science Conference Umm Al-Qurra University Makah, Saudi Arabia April, 14-18th 2012 Southeast University
Speaker, 10th Biennial Microbiology Conference 2015 Punjab University, Lahore Punjab University, Lahore 25-28 March 2015 ASM
Intermediate statistical, scientific writing and producing quality thesis and critical appraisal NJAU Nanjing China 15-19 Dec. 2009 Self

Memberships of Academic Associations

  • Member: Pakistan Society for Biochemistry and Molecular Biology
  • Member: Pakistan Society for Microbiology and American Society for Microbiology
  • Lifelong Registration: Registered Veterinary Medical Practitioner (RVMP)
  • Reviewer for the Pakistan Journal of Zoology
  • Editorial board member: Science letters journal

Students Supervision

MS Thesis:

  1. Nida Andlib: (2017). Detection of Metallo Beta Lactamase Genes in Pseudomonas Aeroginosa From Cancer Patients
  2. Muhammad Murtaza: (2017). Prevalance and Risk Factors Analaysis of Europathogenic Escherichia coli From Clinical Samples in Lahore.
  3. Zubaida Sharif: Isolation and Physical Characterization of JHA Bacteriophage Against Multidrug Resistant Acinetobacter Baumannii.
  4. Sana Zahid: Isolation and Physical Characterization of Bacteriphage against Multidrug Resistant Pseudomonas aeroginosa.
  5. Muhammad Farhan: “Detection of Carbapenem Resistant Metallo-β lactamases Genes among Pseudomonas aeruginosa Strains Isolated From Cancer patients.

MSc Thesis:

  1. Kiran Latif: (2017) Evaluation of serum electrolyte profile in diabetes type 2 female patients.
  2. Kinza Hashan: (2018) Circulating MicroRNAs as a Potential Biomarker for detection of oncogenic viral infection

Publications

Articles citations: 400; H index = 10; Impact Factor = 45
[1] Zeshan B., Sadaf A., NH Othman. (2016). Recent progress in delivery of cancer related MicroRNAs. J. Nanoscience & Nanotechnology, 16:6622-6633.
[2] Zeshan B., S Ahmed., NH Othman. (2014). Construction and identification of a recombinant adenovirus expressing bioactive GM-CSF: Implication for GM-CSF secreting tumor vaccines design. Asian Pacific Journal of Tropical Disease 4 (3), 230.
[3] Zeshan B., Mushtaq M.H., Xinglong W., Wenliang L., Jiang P. (2011). Protective immune responses induced by in ovo immunization with recombinant adenoviruses expressing Spike (S1) glycoprotein of infectious bronchitis virus fused/co-administered with granulocyte macrophage colony stimulating factor. Vet. Microbiol.148:8-17.
[4] Zeshan B., Zhang L., Bai J., Xinglong W., Xu J., Jiang (2010). Immunogenicity and protective efficacy of a replication-defective infectious bronchitis virus vaccine using an adenovirus vector and administered in ovo. J Virol Methods 166:54─9.
[5] Sadaf A., Zeshan B*., Wang Z., Zhang R., Xu S., Wang C., Cui Y. (2012). Toxicity Evaluation of Hydrophilic CdTe Quantum dots and CdTe@SiO2 Nanoparticles in Mice. J. Nanosci. Nanotech. 12(11):8287-92 *Equal contributions.
[6] Sadaf A., Zeshan B., Wang Z., Zhang R., Xu S., Wang C., Yang J., Cui Y. (2012). A Comparative Study of CdTe Quantum Dots and CdTe@SiO2 Nanoparticles: Fabrication and Cytotoxicity in HEK-293 Cells J. Nanosci. Nanotech. 12, 6900-06.
[7] Shi W., Du J., Qi Y., Liang G., Wang T., Li S.,  Xie S., Zeshan B., Xiao Z. (2012). Aberrant expression of serum miRNAs in schizophrenia. J. Psychiatr. Res. 46:198-04.
[8] Waqas Y., Lisi H., Yang P., Shakeeb U., Zhang L., Zhang Q., Li Q., Ahmad N., Chen W., Zeshan B., Qiusheng Chen. (2015). Novel cellular evidence of oviduct secretions in the Chinese soft-shelled turtle Pelodiscus sinensis. Journal of Experimental Zoology, 323A:655–65.
[9] Bai J., Chen X., Kangfu J., Zeshan B., Jiang P. 2014. Identification of VP1 peptides diagnostic of encephalomyocarditis virus from swine. Virology journal 11 (1), 226.
[10] Bi Y., lu L., Li J., Yin Y., Zhang Y., Gao H., Qin Z., Zeshan B., Liu J., Sun L., Liu W. (2011). Novel genetic reassortants in H9N2 influenza A viruses and their diverse pathogenicity to mice. Virol. J. 8:505. doi:10.1186/1743-422X-8-505.
[11]  Zhang K., Wang Z., Liu X., Yin C., Zeshan B., Xia B., Liu W. (2012). Dissection of Influenza A Virus M1 Protein: pH-Dependent Oligomerization of N-Terminal Domain and Dimerization of C-Terminal Domain. PLoS ONE 7(5): e37786. doi:10.1371/journal.pone.0037786.
[12]  Bai J., Jiang K., Zeshan B., Wang X., Li Y., Ping J. (2011). Inhibition of encephalomyocarditis virus replication by shRNA targeting 1D and 3AB genes in vitro and in vi Virus Genes 44:183─90.
[13]  Li J., Jiang, Li Y., Wang X., Cao J., Wang X, Zeshan B. (2009). HSP70 fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus enhanced the immune responses and protective efficacy against virulent PRRSV challenge in pigs. Vaccine 27:825─32.
[14] Wang X., Li J., Jiang P., Li Y., Zeshan B., Cao J., Wang X. (2009). GMCSF fused with GP3 and GP5 of porcine reproductive and respiratory syndrome virus increased the immune responses and protective efficacy against virulent PRRSV challenge. Virus. Res. 143:24─32.
[15] Li G., Jiang P., Li Y., Wang X., Huang J., Du Y., Zeshan B. (2009). Effective suppression of replication of porcine reproductive and respiratory syndrome virus by adenovirus-mediated small interfering RNAs targeting ORF1b, 5 and 7 genes. Virol. Meth. 157:40─6.
[16] Li G., Jiang P., Li Yu., Wang X., Huang J., Bai J., Cao J., Wu B., Chen N., Zeshan B. (2009). Inhibition of porcine reproductive and respiratory syndrome virus replication by adenovirus-mediated RNA interference both in porcine alveolar macrophages and swine. Res. 82:157─65.
[17]  Iqbal M.F., Cheng F.Y., Zhu W.Y., Zeshan B. (2008). Mitigation of ruminant methane production: current strategies, constraints and future options. World J. Microb. Biot. 24:2747─55.
[18]  Zhang Li., Cao G.L., Zeshan B., Li W., Xu J., Wang X., Jiang P. (2009). Identification of one strain of nephropathogenic avian infectious bronchitis virus. Animal Husb Vet Med 41:11─15 (Article in chinese).
[19]  Abdullah, A.F., Zeshan, B., Redhuan, N.E., Mohamed, M., Daud N, H. (2017). Detection of equine herpesvirus infection: conventional versus molecular approaches. J. Animal and Plant Science (Accepte).
[20]  Htoo, N.N., Zeshan B, Khaing, A.T., Kyaw, T., Woldegiorgis, E.A., Azam K. Creep Feeding Supplemented
with Roughages Improve Rumen Morphology in Pre-Weaning Goat Kids (Minor Revision submitted to Pak J Zoology).
[21] Zeshan, B., Mushtaq, A.S., Javed, I.W., Mokhtar, A., Maizan, M. (2017). Cloning, Expression and Immunogenicity of Truncated Spike Glycoprotein (Sf200) of nephropathogenic Infectious Bronchitis Virus (Accepted in Pak J Zoology).
[22] Muhaimin, A., Zeshan, B*, Mohamed, M., Bhandare S. Molecular Survey of Campylobacter Jejuni in in North Eastern Kelantan (Submitted).

dr.basit@ucp.edu.pk
042-35880007 Ext: 451
University of central Punjab Faculty of Life Sciences

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