Mechanical Equipments, Specific formulation consideration and Emulsion stability.
Formulation of suspensions, Equipment used in preparation and test methods for pharmaceutical suspensions
Equipment used for Ointments, Pastes, Gels and Jellies. Packaging of ointments
Equipments Used For
Patches, Sprays, Implants, Sutures, Plasters and Sachet packing
Sterile area and its Classification, Ophthalmic ointments, Preparation of parenterals (Building, Equipment), Complete Sterility (Aseptic area), air control, (Laminar flow etc.), air locks, Environmental monitoring methods, Sterilization, Filling/Packaging (Plastic and glass containers), Added substances (Preservatives, anti-oxidants, solubilizer, suspending agents, buffers, stabilizers etc.), In process Quality Control of Parenterals (Sterility, leakage, pyrogens, clarity etc.).
Packing & Packaging
Influence of Packaging materials, Stability, Packaging Lines, Packaging Area, Packaging Equipment.
Safety Methods In Pharmaceutical Industry
- Mechanical, chemical and fire hazards problems.
- Inflammable gases and dusts.
STUDY TOUR: A visit to the pharmaceutical industries will be an integral part of the syllabus and will prepare and submit a report about operations in Pharmaceutical industry that will be evaluated in practical examination
Practical of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Manufacture of Tablets by Wet Granulation Method, by Slugging and by Direct Compression. Coating of Tablets (Sugar Coating, Film coating and Enteric Coating). Clarification of liquids by various processes. Size Reduction. Homogenization. Ampoule filling, sealing and sterilization clarity and leakage tests in injectables. Capsule filling by semi automatic machines. Manufacture of sustained action drugs. Tablets Tests like Disintegration. Dissolution. Friability. Hardness and thickness tests. Determination of weight variation in tablets. Density of powder. Particle size analysis (Note: A minimum of 10 practicals will be conducted).