Dr. Sumera Zaib

Dr. Sumera Zaib

Assistant Professor

sumera.zaib@ucp.edu.pk
Ext:

Dr. Sumera Zaib has received her M.Phil and PhD degrees in 2010 and 2016 from Hazara University. During her PhD, she has visited University of Bonn, Germany, as a DAAD research fellow. After completing her PhD, Dr. Zaib has worked as a Postdoctoral Research Fellow at COMSATS University Islamabad, Abbottabad Campus from May 2015 to August 2017. Afterwards, she worked as an Assistant Professor (IPFP) at International Islamic University, Islamabad from August 2017 to August 2018. After completing the IPFP tenure successfully, she has joined again COMSATS University Islamabad, Abbottabad Campus as a Postdoctoral Research Fellow from September 2018 to July 2019. She is currently working as an Assistant Professor at Department of Biochemistry, Faculty of Life Sciences, University of Central Punjab, Lahore, from August 2019 to date.

She has successfully produced 2 book chapters and >100 meritorious publications in highly prestigious international journals with h-index of 22 and >300 impact factor with more than 1500 citations. In recognition to her scientific contribution, she has been awarded several research productivity awards by Pakistan Council of Science & Technology (PCST) and COMSATS University, Islamabad. Besides excellent teaching and research output, she has supervised and co-supervised numerous graduate and undergraduate students. Additionally, she has been involved in organizing international and national conferences, workshops, symposia, and for many of which she has served as a resource person and delivered various presentations in both national and international conferences. Her research interests are centered around the protein chemistry and enzymology with special emphasis on the identification of potent structural leads of biological importance. Her group also work on various aspects of clinical biochemistry and enzyme inhibition studies.

PhDBiochemistryHazara University, Mansehra2016
Assistant ProfessorDepartment of Biochemistry, Faculty of Life Sciences, University of Central Punjab, Lahore August 2019 to date
Post doctoral Research AssociateCOMSATS University Islamabad, Abbottabad CampusSeptember 2018 to July 2019
Assistant ProfessorInternational Islamic University, IslamabadAugust 2017 to August 2018
Assistant Professor Abbottabad International Medical College, AbbottabadMay 2016 to July 2017
Senior Research Assistant COMSATS University Islamabad, Abbottabad CampusMay 2015 to August 2017.
Research ScholarCOMSATS University Islamabad, Abbottabad CampusNovember 2010 to April 2015
LecturerAbbottabad International Medical College, AbbottabadJuly 2011 – December 2012
Internee under National Internship Program Hazara University, Mansehra, PakistanJuly 2010 – June 2011
DemonstratorAbbottabad International Medical College, AbbottabadApril 2007 – April 2008
1Amara Mumtaz, Kiran Saeed, Abid Mahmood, Sumera Zaib, Aamer Saeed, Julie Pelletier, Jean Sévigny, Jamshed Iqbal. Synthesis, selective alkaline phosphatases inhibition and molecular docking studies of pimelic acid and 4-methylsalicylic acid derivatives. Bioorganic Chemistry (Accepted) IF=3.926
2Hamid Aziz Wazir, Abid Mahmood, Sumera Zaib, Aamer Saeed, Julie Julie Pelletier, Jean Savigny, Jamshed Iqbal. Synthesis, characterization, alkaline phosphatase inhibition assay and molecular modeling studies of 1-benzylidene-2-(4-tert-butylthiazol-2-yl) hydrazine. Journal of Biomolecular Structure & Dynamics (Accepted) IF=3.31
3Md Yousof Ali, Sumera Zaib, Susoma Jannat, M. Mizanur Rahman, Jamshed Iqbal, Brandon Findlay, Adrian Tsang. Poncirin, an orally active flavonoid exerts antidiabetic complications and improves glucose uptake activating PI3K/Akt signaling pathway in insulin resistant C2C12 cells with anti-glycation capacities. Bioorganic Chemistry (Accepted) IF=3.926
4Aamer Saeed, Ghulam Shabir, Abid Mahmood, Asma Khurshid, Sumera Zaib, Jamshed Iqbal. An Efficient Synthetic Approach Toward a Sporadic Heterocyclic Scaffold: 1,3-Oxathiol-2-ylides; Alkaline Phosphatase Inhibition and Molecular Docking studies. Bioorganic & Medicinal Chemistry Letters 30 (2020) 127238 IF=2.448
5Dana M. Zaher, Mohammed I. El-Gamal, Hany A. Omar, Sarah N. Aljareh, Salma A. Al-Shamma, Aya J. Ali, Sumera Zaib, Jamshed Iqbal. Recent Advances of Alkaline Phosphatases Isoenzymes and Their Inhibitors. Archiv der Pharmazie DOI: 10.1002/ardp.202000011. IF=2.145
6Saghir Abbas, Faisal Rashid, Emine Ulker, Sumera Zaib, Khurshid Ayub, Sana Ullah, Muhammad Arif Nadeem, Sammer Yousuf, Ralf Ludwig, Saqib Ali, Jamshed Iqbal. Anticancer evaluation of a Manganese Complex on HeLa and MCF-7 Cancer Cells: Design, Deterministic Solvothermal Synthesis Approach, Hirshfeld analysis, DNA Binding, Intracellular Reactive Oxygen Species (ROS) Production, Electrochemical Characterization and Density Functional Theory. Journal of Biomolecular Structure & Dynamics 6 (2020) 1-14. IF=3.31
7Noman Javid, Rubina Munir, Faryal Chaudhry, Aqeel Imran, Sumera Zaib, Ayesha Muzaffar, Jamshed Iqbal. Exploiting oxadiazole-sulfonamide hybrids as new structural leads to combat diabetic complications via aldose reductase inhibition. Bioorganic Chemistry 99 (2020) 103852. IF=3.926
8Saif Ullah, Mohammed I. El-Gamal, Sumera Zaib, Hanan S. Anbar, Seyed-Omar Zaraei, Rawan M. Sbenati, Julie Pelletier, Jean Sévigny, Chang-Hyun Oh, Jamshed Iqbal. Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. Bioorganic Chemistry 99 (2020) 103783. IF=3.929
9Behzad Jafari, Saquib Jalil, Sumera Zaib, Sayfidin Safarov, Muattar Khalikova, Djurabay Khalikov, Meirambek Ospanov, Nazym Yelibayeva, Ghazwan Ali Salman, Zharylkasyn A. Abilov, Mirgul Z. Turmukhanova, Sergey N. Kalugin, Peter Ehlers, Abdul Hameed, Jamshed Iqbal, Peter Langer. Synthesis of 2-alkynyl- and 2-amino-12H-benzothiazolo[2,3-b]quinazolin-12-ones and their inhibitory potential against monoamine oxidase A and B. ChemistrySelect rySelect 4 (2019) 137. IF=1.716
10Behzad Jafari, Saquib Jalil, Sumera Zaib, Sayfidin Safarov, Meirambek Ospanov, Muattar Khalikova; Muzafar Isobaev; Nazken Kelzhanova, Nazym Yelibayeva, Zharylkasyn A. Abilov, Mirgul Z. Turmukhanova, Sergey N. Kalugin, Peter Ehlers, Jamshed Iqbal, Peter Langer. Synthesis of 2-aryl-12H-benzothiazolo[2,3-b]quinazolin-12-ones and their activity against monoamine oxidases. ChemistrySelect 4 (2019) 11071–11076. IF=1.716
11Noor Uddin, Faisal Rashid, Saqib Ali, Syed Ahmed Tirmizi, Iqbal Ahmad, Sumera Zaib, Muhammad Zubir, Ali Haider, Muhammad Nawaz Tahir, Jamshed Iqbal. Synthesis, characterization, and anticancer activity of Schiff bases. Journal of Biomolecular Structure & Dynamics 28 (2019) 1-14. IF=3.310
12Pervaiz Ali Channar, Hina Irum, Abid Mehmood, Ghulam Shabir, Sumera Zaib, Aamer Saeed, Muhammad Zaman Ashraf, Fayaz Ali Larik, Joanna Lecka, Jean Sévigny, Jamshed Iqbal. Design, synthesis and biological evaluation of Trinary Benzocoumarin-Thiazoles-Azomethine derivatives as Effective and Selective Inhibitors of Alkaline Phosphatase. Bioorganic Chemistry 91 (2019) 103137. IF=3.926
13Mohammed I. El-Gamal, Saif Ullah, Seyed-Omar Zaraei, Saquib Jalil, Sumera Zaib, Dana M. Zaher, Hany A. Omar, Hanan S. Anbar, Julie Pelletier, Jean Sévigny, Jamshed Iqbal. Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. European Journal of Medicinal Chemistry 181 (2019) 111560. IF=4.833
14Seyed-Omar Zaraei, Mohammed I. El-Gamal, Zainab Shafique, Sayyeda Tayyeba Amjad, Saifullah Afridi, Sumera Zaib, Hanan S. Anbar, Jamshed Iqbal. Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors. Bioorganic & Medicinal Chemistry 27 (2019) 3889–3901. IF=2.802
15Saira Afzal, Sumera Zaib, Behzad Jafari, Peter Langer, Joanna Lecka, Jean Sévigny, Jamshed Iqbal. Highly Potent and Selective Ectonucleoside Triphosphate Diphosphohydrolase (ENTPDase1, 2, 3 and 8) Inhibitors Having 2-substituted-7-trifluoromethyl-thiadiazolopyrimidones Scaffold. Medicinal Chemistry 16 (2020) 1-14. IF=2.530
16Adnan Amin, Muhammad Hanif, Abdul Rafey, Sumera Zaib, Sattar Bakhsh, Muhammad Ramzan, Jamshed Iqbal, Luc Pieters. Inhibition of 15-LOX, α-glucosidase, and in silico molecular docking studies of sesquiterpene coumarins from Ferula narthex exudate. Revista Brasileira de Farmacognosia 30 (2020) 12-17. IF=1.338
17Amara Mumtaz, Abdul Majeed, Sumera Zaib, Shafiq Ur Rahman, Saba Hameed, Aneela Maalik, Aamer Saeed, Hummera Rafique, Ehsan Ullah Mughal, Izhar Hussain, Jamshed Iqbal. Investigation of potent inhibitors of cholinesterase based on thiourea and pyrazole derivatives: Synthesis, inhibition assay and molecular modeling studies. Bioorganic Chemistry DOI: 10.1016/j.bioorg.2019.103036. IF=3.926
18Syeda Shamila Hamdani, Bilal Khan, Shahid Hameed, Faisal Rashid, Sumera Zaib, Khalil Ahmed, Ehsan U Mughal, Jamshed Iqbal. Cytotoxicity, pro-apoptotic activity and in silico studies of dithiocarbamates and their structure based design and SAR Studies. Medicinal Chemistry DOI: 10.2174/1573406415666190211162013 IF=2.530
19Behzad Jafari, Saquib Jalil, Sumera Zaib, Sayfidin Safarov, Muattar Khalikova, Meirambek Ospanov, Nazym Yelibayeva, Zharylkasyn A. Abilov, Mirgul Z. Turmukhanova, Sergey N. Kalugin, Peter Ehlers, Jamshed Iqbal, Peter Langer. Synthesis and Inhibitory activity towards Monoamine Oxidase A and B of 8-functionalized-2-methyl-3-fluoro-benzo[4,5]thiazolo[3,2-a]pyrimidin-4-ones. ChemistrySelect (2019) 4(24): 7284-7291. IF=1.716
20Mohammad H. Semreen, Mohammed I. El-Gamal, Saif Ullah, Saquib Jalil, Sumera Zaib, Chang-Hyun Oh, Joanna Lecka, Jean Sévigny, Jamshed Iqbal. Synthesis, biological evaluation, and molecular docking study of sulfonate derivatives as nucleotide pyrophosphatase (NPPs) inhibitors. Bioorganic & Medicinal Chemistry (2019) 27(13): 2741-2752. IF=2.802
21Hina Andleeb, Shahid Hameed, Syeda Abida Ejaz, Imtiaz Khan, Sumera Zaib, Joanna Lecka, Jean Sévigny, Jamshed Iqbal. Probing the high potency of pyrazolyl pyrimidinetrione and thioxopyrimidinedione conjugates as selective and efficient inhibitors of recombinant human ectonucleotidases: A facile chemical synthesis and computational docking analysis. Bioorganic Chemistry (2019) 88: 102893. IF=3.926
22Saghir Abbas, Sumera Zaib, Shafiq ur Rahman, Saqib Ali, Shahid Hameed, Muhammad Nawaz Tahir, Khurram Shehzad Munawer, Farzana Shaheen, Syed Mustanser Abbas, Jamshed Iqbal. Carbonic anhydrase inhibitory potential of Flurbiprofen, Ibuprofen and 4-Tert-butylbenzoic hydrazide Derivatives: Design, synthesis, characterization, biochemical evaluation, molecular docking and dynamic studies. Medicinal Chemistry (2019) 15(3): 298-310. IF=2.530
23Md Yousof Ali, Sumera Zaib, M. Mizanur Rahman, Susoma Jannat, Jamshed Iqbal, Seong Kyu Park, Mun Seog Chang. Didymin, a dietary citrus flavonoid exhibits anti-diabetic complications and promotes glucose uptake through the activation of PI3K/Akt signaling pathway in insulin-resistant HepG2 cells. Chemico-Biological Interactions (2019) 305: 180-194. IF= 3.407
24Komal Hayat, Saira Afzal, Altaf Saeed, Amna Murtaza, Shafiq ur Rahman, Khalid Khan, Aamer Saeed, Sumera Zaib, Joanna Lecka, Jean Sevigny, Jamshed Iqbal, Abbas Hassan. Investigation of new quinoline derivatives as promising inhibitors of NTPDases: Synthesis, SAR analysis and molecular docking studies. Bioorganic Chemistry (2019) 87: 218-226. IF=3.926
25Gabriel O. Anyanwu, Chukwu E. Onyeneke, Okoli, B. J., Johannes, M. S., Sabi-ur-Rehman, Jamshed Iqbal, Syeda Abida Ejaz, Sumera Zaib, Khalid Rauf, Nisar-ur-Rehman. Pharmacological Activities of a Novel Phthalic Acid Ester and Iridoid Glycoside Isolated from the Root Bark of Anthocleista vogelii Planch. Tropical Biomedicine (2019) 36(1): 35-43. IF=0.418
26Shakeel Ahmad, Saquib Jalil, Sumera Zaib, Sana Aslam, Matloob Ahmad, Azhar Rasul, Muhammad Nadeem Arshad, Sadia Sultan, Abdul Hameed, Abdullah M. Asiri, Jamshed Iqbal. Synthesis, X-ray crystal and monoamine oxidase inhibitory activity of 4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine 5,5-dioxides: In vitro studies and docking analysis. European Journal of Pharmaceutical Sciences (2019) 131: 9–22. IF=3.532
27Gabriel Anyanwu, Jamshed Iqbal, Shafi Ullah Khan, Sumera Zaib, Khalid Rauf, Chukwu E. Onyeneke, Opeolu O. Ojo, Nisar Rahman. Antidiabetic activities of chloroform fraction of Anthocleista vogelii Planch root bark in rats with diet-induced obesity-diabetes. Journal of Ethnopharmacology (2019) 229: 293–302. IF=3.414
28Azhar Abbas, Basharat Ali, Kanwal, Khalid Mohammed Khan, Jamshed Iqbal, Shafiq ur Rahman, Sumera Zaib, Shahnaz Perveen. Synthesis and in vitro urease inhibitory activity of benzohydrazide derivatives, in silico and kinetic studies. Bioorganic Chemistry (2019) 82: 163-177. IF=3.926
29Behzad Jafari, Faisal Rashid, Saifidin Safarov, Meirambek Ospanov, Nazym Yelibaeva, Zharylkasyn Abilov, Mirgul Turmukhanova, Sergei Kalugin, Peter Ehlers, Muhammad I Umar, Sumera Zaib, Jamshed Iqbal, Peter Langer. Synthesis of novel benzothiazolo[3,2-a]pyridimidin-4-ones with potential cytotoxic and pro-apoptotic potential. ChemistrySelect (2018) 3: 12213– 12218. IF=1.716
30Jamshed Iqbal, Muhammad Shakeel Ahmad Abbasi, Sumera Zaib, Saifullah Afridi, Norbert Furtmann, Jürgen Bajorath, Peter Langer. Identification of new chromenone derivatives as cholinesterase inhibitors and molecular docking studies. Medicinal Chemistry (2018) 14: 809-817. IF=2.530
31Shakeel Ahmad, Sumera Zaib, Saquib Jalil, Muhammad Shafiq, Matloob Ahmad, Sadia Sultan, Mazher Iqbal, Sana Aslam, Jamshed Iqbal. Synthesis, characterization, monoamine oxidase inhibition, molecular docking and dynamic simulations of novel 2,1-benzothiazine-2,2-dioxide derivatives. Bioorganic Chemistry (2018) 80: 498-510. IF=3.926
32Wassim W. Ayass, Tamás Fodor, Edit Farkas, Zhengguo Lin, Hafiz M. Qasim, Saurav Bhattacharya, Ali S. Mougharbel, Khaled Abdallah, Matthias S. Ullrich, Sumera Zaib, Jamshed Iqbal, Sándor Harangi, Gábor Szalontai, István Bányai, László Zékány, Imre Tóth, Ulrich Kortz. Di-Thallium(III)-Containing 30-Tungsto-4-Phosphate, [Tl2Na2(H2O)2(P2W15O56)2]16-: Synthesis, Structural Characterization, and Biological Studies. Inorganic Chemistry (2018) 57(12): 7168-7179. IF=4.850
33Muhammad Riaz Khan, Sumera Zaib, Muhammad Khawar Rauf, Amin Badshah, Muhammad Nawaz Tahir, Azim Khan, Jamshed Iqbal. Pd(II)-based heteroleptic complexes with N-(acyl)-N′, N′-(disubstituted)thioureas and Phosphine ligands: Synthesis, characterization and cytotoxic studies against lung squamous, breast adenocarcinoma and Leishmania tropica. Inorganica Chimica Acta (2018) 479(1): 189–196. IF=2.433
34Adewole Ezekiel, Sumera Zaib, Ojo Abiodun, Onasanya Amos, Jamshed Iqbal. GC-MS analysis and antidiabetic potentials of Bridelia Micrantha crude extracts. Integrative Molecular Medicine (2018) 5(4): 1-5. IF=2.01
35Adewole E, Ojo A, Omoaghe AO, Enye LA, Sumera Zaib. Aldose Reductase Inhibitory Effect and Identification of Bioactive Compounds in Carica Papaya Extract Der Pharmacia Lettre, (2018) 10(20): 73-78.
36Muhammad Riaz Khan, Sumera Zaib, Muhammad Khawar Rauf, Masahiro Ebihara, Amin Badshah, Muhammad Zahid, Muhammad Arif Nadeem, Jamshed Iqbal. Solution-phase microwave assisted parallel synthesis of N-aroyl-N´-aryl thioureas: biological evaluation and in silico docking studies. Journal of Molecular Structure (2018) 1164: 354-362. IF=2.120
37Amara Mumtaz, Muhammad Shoaib, Sumera Zaib, Muhammad Shakil Shah, Huma Aslam Bhatti, Aamer Saeed, Izhar Hussain, Jamshed Iqbal. Synthesis, molecular modelling and biological evaluation of tetrasubstituted thiazoles towards cholinesterase enzymes. Bioorganic Chemistry (2018) 78: 141-148. IF=3.926
38Humayun Pervez, Nazia Khan, Jamshed Iqbal, Sumera Zaib, Muhammad Yaqub, Muhammad Moazzam Naseer. Synthesis and in vitro bio-activity evaluation of N4-benzyl substituted 5-chloroisatin 3-thiosemicarbazones as urease and glycation inhibitors. Acta Chim Slov (2018) 65: 108–118. IF=1.076
39Guy Sedar Singor Njateng, Sumera Zaib, Larissa Yetenge Chimi, Cesaire Feudjio, Raymond Simplice Mouokeu, Donatien Gatsing, Jules-Roger Kuiate, Ezekiel Adewole, Jamshed Iqbal. Antidiabetic potential of methanol extracts from leaves of Piper umbellatum L. and Persea americana Mill. Asian Pacific Journal of Tropical Biomedicine (2018) 8(3): 160-165. IF=1.587
40Humayun Pervez, Nazia Khan, Jamshed Iqbal, Sumera Zaib, Muhammad Yaqub, Muhammad Nawaz Tahir, Muhammad Moazzam Naseer. Synthesis, crystal structure, molecular docking studies, and in vitro bio-evaluation of some N4-benzyl substituted isatin-3-thiosemicarbazones as potent antiurease and antiglycating agents. Heterocyclic Communications (2018) 24: 51–58. IF=0.810
41Nehal Afreen Khan, Imtiaz Khan, Syed Mobasher Ali Abid, Sumera Zaib, Aliya Ibrar, Hina Andleeb, Shahid Hameed, Jamshed Iqbal. Quinolinic Carboxylic Acid Derivatives as Potential Multi-target Compounds for Neurodegeneration: Monoamine Oxidase and Cholinesterase Inhibition. Medicinal Chemistry (2018) 14: 74-85. IF=2.530
42Mariia Miliutina, Julia Janke, Sidra Hassan, Sumera Zaib, Jamshed Iqbal, Joanna Lecka, Jean Sévigny, Alexander Villinger, Aleksej Friedrich, Stefan Lochbrunner, Peter Langer. Domino Reaction of 3-Chlorochromones with Aminoheterocycles. Synthesis of Pyrazolopyridines and Benzofuropyridines and their Optical and Ecto-5'-nucleotidase Inhibitory Effects. Organic and Biomolecular Chemistry (2018) 16: 717-732. IF=3.490
43Madiha Kazmi, Sumera Zaib, Aliya Ibrar, Sayyeda Tayyeba Amjad, Imtiaz Khan, Zainab Shafique, Aamer Saeed, Jamshed Iqbal. A New Entry into the Portfolio of α-Glucosidase Inhibitors as Potent Therapeutics for Type 2 Diabetes: Design, Bioevaluation and One-pot Multi-component Synthesis of Diamine-bridged Coumarinyl Oxadiazole conjugate. Bioorganic Chemistry (2018) 77: 190-202. IF=3.926
44Saghir Abbas, Hafiza Huma Nasir, Sumera Zaib, Saqib Ali, Tariq Mahmood, Khurshid Ayub, Muhammad Nawaz Tahir, Jamshed Iqbal. Carbonic anhydrase inhibition of schiff base derivative of imino-methyl-naphthalen-2-ol: Synthesis, structure elucidation, molecular docking, dynamic simulation and density functional theory calculations. Journal of Molecular Structure (2018) 1156: 193-200. IF=2.12
45Furqan Ahmad Siddique, Sumera Zaib, Saquib Jalil, Sana Aslam, Matloob Ahmad, Sadia Sultan, Humera Naz, Mazher Iqbal, Jamshed Iqbal. Synthesis, biological evaluation and molecular docking studies of novel 4-hydroxy-N'-[benzylidene or 1-phenylethylidene]-2-H/methyl/benzyl/-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides. European Journal of Medicinal Chemistry (2018) 143: 1373-1386. IF=4.833
46Aliya Ibrar, Sumera Zaib, Zainab Shafique, Imtiaz Khan, Aamer Saeed, Jamshed Iqbal. New prospects for the development of selective inhibitors of α-glucosidase based on coumarin-iminothiazolidinone hybrids: Synthesis, in-vitro biological screening and molecular docking analysis. Journal of the Taiwaan Institute of Chemical Engineers (2017) 81: 119-133. IF=3.849
47Shaista Parveen, Muhammad Shakil Shah, Sumera Zaib, Tayyaba Gul, Khalid M. Khan, Abbas Hassan, Jamshed Iqbal. Modification of Bischler Mohlau Indole Derivatives through Palladium Catalyzed Suzuki Reaction as Effective Cholinesterase Inhibitors, their Kinetics and Molecular Docking Studies. Bioorganic Chemistry (2017) 76: 166–176. IF=3.926
48Madiha Kazmi, Sumera Zaib, Sayyeda Tayyeba Amjad, Imtiaz Khan, Aliya Ibrar, Aamer Saeed, Jamshed Iqbal. Exploration of aroyl/heteroaroyl iminothiazolines featuring 2,4,5-trichlorophenyl moiety as a new class of potent, selective, and in-vitro efficacious glucosidase inhibitors. Bioorganic Chemistry (2017) 74: 134–144 IF=3.926
49Nazar Ul Islam, Raza Amin, Muhammad Shahid, Muhammad Amin, Sumera Zaib, Jamshed Iqbal. A multi-target phytotherapeutic potential of Prunus domestica stabilized nanoparticles acquired prospective anticancer, antibacterial, urease-inhibition, anti-inflammatory and analgesic properties. BMC Complementary and Alternative Medicine (2017) 17: 276-293. IF=2.479
50Syed Mobasher Ali Abid, Sana Aslam, Sumera Zaib, Syeda Mahwish Bakht, Matloob Ahmad, John M Gardiner, Jamshed Iqbal. Pyrazolobenzothiazine-based carbothioamides as new structural leads for the inhibition of monoamine oxidases: design, synthesis, in-vitro bioevaluation and molecular docking studies. Medicinal Chemical Communications. (2017) 8: 452-464. IF=2.394
51Naeem Abbas, Sumera Zaib, Syeda Mahwish Bakht, Aliya Ibrar, Imtiaz Khan, Sadaf Batool, Aamer Saeed, Jamshed Iqbal. Symmetrical aryl linked bis-iminothiazolidinones as new chemical entities for the treatment of Parkinson's disease: synthesis, in-vitro monoamine oxidase inhibition and molecular modelling analysis. Bioorganic Chemistry (2017) 70: 17-26. IF=3.926
52Amara Mumtaz, Fareeha Zahoor, Sumera Zaib, Azhar Nawaz, Aamer Saeed, Amir Waseem, Afsar Khan, Izhar Hussain. Jamshed Iqbal. Synthesis, characterization and biological activities of the creatinine amides and creatinine Schiff bases. Medicinal Chemistry (2017) 13(2): 196-203. IF=2.530
53Humayun Pervez, Nazia Khan, Sumera Zaib, Muhammad Yaqub, Muhammad Moazzam Naseer, Muhammad Nawaz Tahir, Jamshed Iqbal. Synthesis, X-ray molecular structure, biological evaluation and molecular docking studies of some N4-benzyl substituted 5-nitroisatin 3-thiosemicarbazones. Bioorganic and Medicinal Chemistry (2017) 25: 1022–1029. IF=2.802
54Muhammad Khawar Rauf, Sumera Zaib, Ammara Talib, Masahiro Ebihara, Amin Badshah, Michael Bolte, Jamshed Iqbal. Solution-phase microwave assisted parallel synthesis, biological evaluation and molecular docking studies of N,N'-disubstituted thioureas derived from 3-chlorobenzoic acid. Bioorganic and Medicinal Chemistry (2016) 24: 4452-4463. IF=2.802
55Kishwar Sultana, Sumera Zaib, Najm ul Hassan Khan, Imtiaz Khan, Khadija Shahid, Jim Simpson, Jamshed Iqbal. Exploiting the potential of aryl acetamide derived Zn(II) complexes in medicinal chemistry: Synthesis, structural analysis, assessment of biological profile and molecular docking studies. New Journal of Chemistry (2016) 40: 7084-7094. IF=3.069
56Maqbool Ahmad, Humayun Pervez, Sumera Zaib, Muhammad Yaqub, Muhammad Moazzam Naseer, Shafi Ullah Khan, Jamshed Iqbal. Synthesis, biological evaluation and docking studies of some novel isatin-3-hydrazonothiazolines. RSC Advances (2016) 6: 60826– 60844. IF=3.049
57Aliya Ibrar, Sumera Zaib, Farukh Jabeen, Jamshed Iqbal, Aamer Saeed. Unravelling the alkaline phosphatase inhibition, anticancer and antileishmanial potential of coumarin-triazolothiadiazine hybrids: design, synthesis and molecular docking analysis. Archiv der Pharmazie (2016) 349: 553–565 IF=2.145
58Humayun Pervez, Maqbool Ahmad, Sumera Zaib, Muhammad Yaqub, Muhammad Moazzam Naseer, Jamshed Iqbal. Synthesis, cytotoxic and urease inhibitory activities of some novel isatin-derived bis-Schiff bases and their copper (II) complexes. Medicinal Chemistry Communications (2016) 7: 914 – 923 IF=2.394
59Imtiaz Khan, Sumera Zaib, Sadaf Batool, Naeem Abbas, Zaman Ashraf, Jamshed Iqbal, Aamer Saeed. Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification. Bioorganic and Medicinal Chemistry (2016) 24: 2361-2381. IF=2.802
60Samad Yaseen, Muhammad Khawar Rauf, Sumera Zaib, Amin Badshah, Muhammad Irshad Ali, Muhammad Nawaz Tahir, Jamshed Iqbal. Synthesis, Characterization and Urease Inhibition, in vitro Anticancer and Antileishmanial Studies of Co(III) Complexes with N,N,N′ -Trisubstituted acylthioureas. Inorganica Chimica Acta (2016) 443: 69–77. IF=2.433
61Aliya Ibrar, Sumera Zaib, Imtiaz Khan, Farukh Jabeen, Jamshed Iqbal, Aamer Saeed. Facile and expedient access to bis-coumarin-iminothiazole hybrids by molecular hybridization approach: synthesis, molecular modelling and assessment of alkaline phosphatase inhibition, anticancer and antileishmanial potential. RSC Advances (2015) 5: 89919-89931. IF=3.049
62Aamer Saeed, Sumera Zaib, Saba Ashraf, Javeria Iftikhar, Muhammad Muddassar, Kam Y. J. Zhang, Jamshed Iqbal. Synthesis, Cholinesterase Inhibition and Molecular Modeling Studies of Coumarin Linked Thioureas Derivatives. Bioorganic Chemistry (2015) 63: 58-63. IF=3.926
63Najm Ul Hassan Khan, Sumera Zaib, Kishwar Sultana, Imtiaz Khan, Berline Mougang-Soume, Humaira Nadeem, Mukhtiar Hassan, Jamshed Iqbal. Metal Complexes of Tosyl Sulfonamides: Design, X-ray structure, Biological Activities & Molecular Docking Studies. RSC Advances. (2015) 5, 30125-30132. IF=3.049
64Jamshed Iqbal, Sumera Zaib, Aamer Saeed, Muhammad Muddassar, 'Biological Evaluation of Halogenated Thioureas as Cholinesterases Inhibitors against Alzheimer’s Disease & Molecular Modeling Studies', Letters in Drug Design & Discovery, (2015) 12, 488-94. IF=0.953
65Sumera Zaib, Syed Umar Farooq Rizvi, Sana Aslam, Matloob Ahmad, Mariya al-Rashida, Jamshed Iqbal. Monoamine oxidase inhibition & Molecular Modelling studies of Piperidyl-thienyl & 2-Pyrazoline derivatives of Chalcones. Medicinal Chemistry. (2015) 11, 497-505. IF=2.530
66Sumera Zaib, Syed Umar Farooq Rizvi, Sana Aslam, Matloob Ahmad, Syed Mobasher Ali Abid, Mariya al-Rashida, Jamshed Iqbal. Quinolyl-Thienyl Chalcones as Monoamine Oxidase inhibitors and their In Silico Modeling Studies. Medicinal Chemistry. (2015) 11, 580-589. IF=2.530
67Muhammad Sirajuddin, Saqib Ali, Sumera Zaib, Jamshed Iqbal, Muhammad Nawaz Tahir, Taibi Ben Hadd. Design, structural and spectroscopic elucidation and in vitro antimicrobial, anticancer, antileishmanial, urease inhibition activities and interaction with SS-DNA of newly synthesized amide based carboxylic acid. Inorganica Chimica Acta. (2015) 427, 178-187. IF=2.433
68Imtiaz Khan, Syeda Mahwish Bakht, Aliya Ibrar, Saba Abbas, Shahid Hameed, Jonathan M. White, Usman Ali Rana, Salah Ud-Din Khan, Sumera Zaib, Mohammad Shahid, Jamshed Iqbal. Exploration of a library of triazolothiadiazole and triazolothiadiazine compounds as a highly potent and selective family of cholinesterase and monoamine oxidase inhibitors: Design, synthesis, X-ray diffraction analysis and molecular docking studies. RSC Advances. (2015) 5, 21249-21267. IF=3.049
69Muhammad Khawar Rauf, Samad Yaseen, Amin Badshah, Sumera Zaib, Raffia Arshad, Imtiaz-ud-Din, Muhammad Nawaz Tahir, Jamshed Iqbal. Synthesis, Characterization and Urease Inhibition, In Vitro Anticancer and Antileishmanial Studies of Ni (II) Complexes With N,N,N'-Trisubstituted Thioureas. Journal of Biological Inorganic Chemistry (2015) 20(3), 541-54. IF=3.632
70Muhammad Sirajuddin, Saqib Ali, Vickie McKee, Sumera Zaib, Jamshed Iqbal. Organotin (IV) carboxylate derivatives as a new addition to anticancer and antileishmanial agents: Design, physicochemical characterization and interaction with Salmon sperm DNA. RSC Advances. (2014) 4(101), 57505–57521. IF=3.049
71Imtiaz Khan, Aliya Ibrar, Sumera Zaib, Sarfraz Ahmad, Norbert Furtmann, Shahid Hameed, Jim Simpson, Jürgen Bajorath, Jamshed Iqbal. Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: Synthesis, crystal structure determination, cholinesterase inhibitory activity, and binding mode analysis. Bioorg. Med. Chem. (2014) 22(21):6163-73. IF=2.802
72Sana Aslam, Sumera Zaib, Matloob Ahmad, John M. Gardiner, Aqeel Ahmad, Abdul Hameed, Norbert Furtmann, Michael Gütschow, Jürgen Bajorath, Jamshed Iqbal. Novel structural hybrids of pyrazolobenzothiazines with benzimidazoles as cholinesterase inhibitors. Eur. J. Med. Chem. (2014) 78:106-117. IF=4.833
73Sumera Zaib, Aamer Saeed, Karin Stolte, Ulrich Flörke, Mohammad Shahid, Jamshed Iqbal. New aminobenzenesulfonamide-thiourea conjugates: Synthesis and Carbonic anhydrase inhibition and docking studies. Eur. J. Med. Chem. (2014) 78:140-150. IF=4.833
74Imtiaz Khan, Sumera Zaib, Aliya Ibrar, Nasim Hasan Rama, Jim Simpson, Jamshed Iqbal. Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines. Eur. J. Med. Chem. (2014) 78:167-177. IF=4.833
75Aamer Saeed, Pervez A. Mahesar, Sumera Zaib, Muhammad Siraj Khan, Abdul Matin, Jamshed Iqbal. Synthesis, cytotoxicity and molecular modeling studies of new phenylcinnamide derivatives as potent inhibitors of cholinesterases. Eur. J. Med. Chem. (2014) 78: 43-53. IF=4.833
76Afsar Khan, Umar Farooq, Fateh Ullah, Jamshed Iqbal, Ather Farooq Khan, Sumera Zaib, Abdur Rahman Khan, Ali Azarpira. Determination of biological activities and total phenolic contents of flowers of Jasminum humile and roots of Dorema aucheri. Journal of the Chemical Society of Pakistan. (2014) 36(2): 291-295. IF=0.393
77Muhammad Khawar Rauf, Ammara Talib, Amin Badshah, Sumera Zaib, Khurram Shoaib, Mohammad Shahid, Ulrich Flörke, Imtiaz-ud-Din, Jamshed Iqbal. Solution-phase microwave assisted parallel synthesis of N,N'-disubstituted thioureas derived from benzoic acid: biological evaluation and molecular docking studies. Eur. J. Med. Chem. (2013) 70:487-496. IF=4.833
78Aamer Saeed, Sumera Zaib, Arshid Pervez, Amara Mumtaz, Mohammad Shahid, Jamshed Iqbal. Synthesis, molecular docking studies, and in vitro screening of sulfanilamide-thiourea hybrids as antimicrobial and urease inhibitors. Med. Chem. Res. (2013) 22, 3653–3662. IF=1.720
79Farzana Perveen, Sumera Zaib. Phytochemical and Spectrophotometric Analyses of the Hill Toon, Cedrela serrata Royle Methanolic Leaves Extract and Its Fractions. International Journal of Agriculture Innovations and Research. (2013) 1(5): 140-145.
80Muhammad Rizwan Maqsood, Muhammad Hanif, Muhammad Rafiq, Muhammad Saleem, Sumera Zaib, Aftab Ahmed Khan, Mazhar Iqbal, Jamshed Iqbal, Nasim Hasan Rama, Sung-Yum Seo, Ki-Hwan Lee. Some Pyridyl- and Thiophenyl- Substituted 1,2,4-Triazolo[3,4-b]1,3,4-thiadiazole Derivatives as Potent Antibacterial. Bull. Korean Chem. Soc. (2012) 33: 4180-4184. IF=0.602
81Muhammad Hanif, Khurram Shoaib, Muhammad Saleem, Nasim Hasan Rama, Sumera Zaib, Jamshed Iqbal. Synthesis, Urease Inhibition, Antioxidant, Antibacterial and Molecular Docking Studies of 1,3,4-Oxadiazole Derivatives. ISRN Pharmacology. (2012) 928901, 2012.
82Jamshed Iqbal, Sumera Zaib, Umar Farooq, Afsar Khan, Irum Bibi, Saba Suleman. Antioxidant, Antimicrobial and free radical scavenging potential of arial parts of Periploca aphylla and Ricinus communis. ISRN Pharmacology, (2012) 563267, 2012.
83Muhammad Hanif, Muhammad Saleem, Muhammad T. Hussain, Nasim H. Rama, Sumera Zaib, Muhammad Adil M. Aslam, Peter G. Jones, Jamshed Iqbal. Synthesis, Urease Inhibition, Antioxidant and Antibacterial Studies of Some 4-Amino-5-aryl-3H-1,2,4-triazole-3-thiones and their 3,6-Disubstituted 1,2,4-Triazolo[3,4-b]1,3,4-thiadiazole Derivatives. J. Braz. Chem. Soc. (2012) 23, 854-860. IF=1.335
84Farzana Perveen, Sumera Zaib, Irshad, S. Mukhtiar Hassan. Antioxidant and DNA protection activities of the hill toon, Cedrela serrata (Royle) leaves extract and its fractions. Journal of Natural Products, (2012) 5: 207-213. IF=0.527

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